[10], "Blue-skinned family baffled science for 150 years", "Fugates of Kentucky: Skin Bluer than Lake Louise", "Blue People Look for Genetic Connection to Kentucky Fugates", https://en.wikipedia.org/w/index.php?title=Blue_Fugates&oldid=1133437983, This page was last edited on 13 January 2023, at 20:18. Morgellons disease: Analysis of a population with clinically confirmed microscopic subcutaneous fibers of unknown etiology. The number of cases related toinfectionis small, however, and there is no evidence that thesebacteriadirectly cause Morgellons disease. Contact your doctor if you develop a bluish tint to your skin, lips, fingertips, or fingernails that cant be explained by bruising and doesnt go away. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. Diagnosis is made through blood tests and chest x-ray. In James Camerons 2009 blockbuster "Avatar," the forest-loving Navi have stunning blue skin. They have caused me to have livedoid vasculopathy all over my body. If you work in silver mining, processing, or manufacturing, or another field that brings you into regular contact with silver, you may breathe in silver particles or they may become lodged in your skin, causing argyria. Eye Drop Usage. Mucus builds up in these airways and can get infected, causing a pneumonia. People with EPP who also have liver disease require specialist medical treatment and possibly a livertransplant. The main symptom of elastoderma is loose skin that sags or hangs in folds. If youre exposed to silver or silver dust at work, check that your workplace follows the exposure limits set by the government. The results of genetic crosses derived from Punnet squares assume that each gamete contains one allele for each trait, which come from Mendel's law of ____________ , and that . Tell your doctor about any medications, dietary supplements, or treatments youve used that contain silver, and any other exposure to silver. Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. Many causes of blue skin can be addressed at a regular appointment rather than in the emergency room. Keep the immune system healthy through good diet and sleep habits, not smoking, and frequent handwashing. Atopicdermatitis is present in 50% of people with ichthyosis vulgaris (and 8% of those with atopic eczema have the features of ichthyosis vulgaris). When atopic dermatitis is associated with severe ichthyosis vulgaris, the dermatitis tends to be early in onset, severe, and more likely topersistinto adulthood. Going HAM on eyedrops every day is not a good idea. Be sure to finish all the medication, even if you start to feel better. National Organization for Rare Disorders. . It is an autosomal disease caused by genetic mutations. Argyria is a condition in which the skin or mucous membranes turn blue or gray. conditions of autosomal recessive. Blau syndrome, the prototypic auto-inflammatory granulomatous disease. Acral peeling skin syndrome is caused by a mutation in the TGM5 gene, which provides instructions for making anenzymecalled transglutaminase 5, a component of the outer layer of skin. TGM5gene mutations reduce the production of transglutaminase 5, which allows the outermost cells of the epidermis to separate easily from the underlying skin and peel off. Some people get blue skin through another route: silver poisoning, known as argyria. Research has found that the prevalence of pemphigus is quite low in the United States at only 5.2 cases per 100,000 adults. You can prevent argyria by limiting your use of medications that contain silver and avoiding dietary supplements that contain silver. Orphanet. Although hidradenitis suppurativa is a rare skin disorder, affecting up to 2% of the population in the United States and Canada, with the majority of cases presenting in women. Blue baby syndrome, also known as infant methemoglobinemia, is a condition where a baby's skin turns blue. Depending on the cause, cyanosis may develop suddenly, along with shortness of breath and other symptoms. Research has found that Morgellons disease could actually be a tick-borne illness and is associated with Lyme disease. Exposure to silver can take place through occupational exposure like workers involved in silver mining, taking medications with silver salts such as eye drops, using colloidal silver supplements like those for arthritis and diabetes, and during certain surgical and dental procedures involving silver sutures and silver dental fillings. In methemoglobinemia, the hemoglobin is unable to release oxygen effectively to body tissues. Smoking can cause cataracts to form at an early age, which may or may not be able to be removed with surgery. Afamelanotide has been reported to be effective for EPP. Acral peeling skin syndrome is not associated with any other health problems, and generally doesn't significantly impair quality of life. The whites of your eyes and nail beds may also turn blue-gray. The affected areas typically heal without scarring. Clin Cosmet Investig Dermatol. Your hands can turn blue due to a low level of oxygen in the body, caused by a problem with the lungs or heart. Some causes of cyanosis are difficult to prevent. "I have lupus and antiphospholipid syndrome (APS). This peeling is most noticeable on the hands and feet because these areas are more frequently exposed to moisture and friction. Hemoglobin. DermNet NZ. Elastoderma. Other skin disorders that can cause pruritus include dry skin, advanced age, sunburns or an increased sensitivity to sunlight, insect bites, and infestations of mites or lice . There are, however, some skin conditions that are so rare and severe that they require specialized medical treatment. Some foods may trigger the onset of more sores, including garlic, onions, and leeks. The main symptom of pemphigus is blisters on the skin that rupture and become open sores. Depending on your skin color, these color changes may be harder or easier to see. In genetic cases of methemoglobinemia, the recessive gene for the disorder must be passed on by both parents. Visible changes are mild in most cases. Any exposed skin. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, 6 Minutes of Exercise May Protect Brain From Alzheimer's, 'Disturbing' Rate of Adverse Events During Hospital Stays. Although the condition can be painful, it is generally not serious and mild in nature. The content available on buoy.com is not a substitute for professional medical advice, diagnosis, or treatment. Itchy skin is the most common symptom of eczema. Rashes are typically caused by a reaction to a pathogen. Complications may include seizures and heart arrhythmias.. Methemoglobinemia can be due to certain medications, chemicals, or food or it can be inherited. In methemoglobinemia, the hemoglobin is unable to carry oxygen and it also makes it difficult for unaffected hemoglobin to release oxygen effectively to body tissues. Some experts believe that it could be linked to genetics, issues within the immune function, and hormones. Why Doesn't the U.S. Have at-Home Tests for the Flu? National Organization for Rare Disorders. Dermatitis. If you have darker skin, cyanosis may be easier to see in your lips, gums, nails and around your eyes. Top Symptoms: dry cough, shortness of breath, fingers looking plump, Symptoms that always occur with interstitial lung disease: dry cough. The likelihood of having a rare skin disorder is 25% if both parents pass down the gene. If only one parent has the gene, its unlikely that the condition will develop. We avoid using tertiary references. 2017;153(8):760-764. doi:10.1001/jamadermatol.2017.0201, Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C, Crowell K, Eisen DB, Gottlieb AB, Hamzavi I, Hazen PG, Jaleel T, Kimball AB, Kirby J, Lowes MA, Micheletti R, Miller A, Naik HB, Orgill D, Poulin Y. People with this condition may experience symptoms when exercising, such as headaches and shortness of breath, due to the lower oxygen level in the blood. Hemoglobin is the molecule in red blood cells that distributes oxygen to the body. North American clinical management guidelines for hidradenitis suppurativa: Apublication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. Under-oxygenated blood is bluer and causes your skin to look. The cause of elastoderma is largely unknown. When Adderall is misused or taken in greater quantity than the recommended dose, a whole new set of skin problems is possible, according to Gil Yosipovitch, M.D., director of the Miami Itch Center . A fall or bump can result in a bruise, where small blood vessels are damaged and leak blood (ecchymosis). Protect your heart, blood vessels, and respiratory system by avoiding smoking and second-hand smoke and exercising regularly. Slide the LOCK button to unlock or lock. National Center for Advancing Translational Sciences. The word cyanosis comes from the word cyan. Casey Gallagher, MD, is board-certified in dermatology. If silver builds up in the body over a long time, it can cause a condition called argyria. Some people's internal organs in their abdomen -- such as the spleen, liver, and intestines -- take on a bluish color, but you wouldnt know this unless you had surgery. 2013;88(3):413-6. doi:10.1590/abd1806-4841.20131864, Griffith RD, Simmons BJ, Bray FN, Falto-Aizpurua LA, Yazdani Abyaneh MA, Nouri K. 1064nm Q-switched Nd:YAG laser for the treatment of Argyria: a systematic review. There is no cure for Argyria, but some treatment options are available for those with the disorder. 2010;3:67-78. doi:10.2147/ccid.s9520, Sachar M, Anderson KE, Ma X. Protoporphyrin IX: the Good, the Bad, and the Ugly. Makers of these products may claim they boost your immune system and can treat cancer, HIV and AIDS, shingles, herpes, and eye problems, but scientific research doesnt support that. Hadjiliadis D. Blue Discoloration of the Skin. This pet nail clipper with LED light allows your dog or cat to easily enjoy the manicure process! Although "hidradenitis" implies an inflammatory disorder of sweatglands, research has shown that hidradenitis suppurativa is anautoinflammatorysyndrome., Associations and risk factors include:, There are two main treatment options for Hidradenitis suppurativa: medication and surgery. Raynauds disease. Dry skin, also known as xerosis or xeroderma, has many causes, including cold or dry weather, sun damage, harsh soaps, and overbathing. Also avoid foods that can cause irritation in the mouth like foods that are high in acids, spicy, or hard. Or you may get blue hands after spending time outside in cold weather. Eczema - Vitamin B3 Deficiency Niacin is vital as it's required for the body to convert fat, protein, and carbohydrates into energy. Notice the skin around your childs mouth turning blue? Research has suggested that it is a cutaneous form of rheumatoid arthritis. heart abnormalities (present during birth). Many conditions can cause your skin to have a bluish tint. It is approved for the treatment of EPP under orphan drug status. 2015;90(3):391-3. doi:10.1590/abd1806-4841.20153263. Numerous skin areas, including the face, upper chest, armpits, and groyne, are susceptible to developing . Laser therapy may also help treat argyria. Other symptoms include:. Its also more noticeable on light colored skin. Itchy and flaking skin are potential side effects of this illness. 5 2016;356(2):267-75. doi:10.1124/jpet.115.228130. Symptoms of this rare disease can include: Another disorder that is known to cause the skin to turn to a bluish or silver hue is argyria. WebMD does not provide medical advice, diagnosis or treatment. It may only affect one area of skin, or it could change the appearance of all your skin. Typically, the best time to apply creams is when the skin is moist following a bath. Central Cyanosis is a blue discoloration seen on the tongue and lips, and is due to lower levels of oxygen in the Central arterial blood; caused by cardiac or respiratory disorders. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. A COPD (chronic obstructive pulmonary disease) exacerbation is a worsening of your COPD, causing you to struggle for breathe. These data were collected by the Centers for Disease Control and Prevention (CDC) during a study with 3.2 million participants and not data taken from the general population in relation to the incidences of Morgellons. Am J Dermatopathol. Erythropoietic protoporphyria (EPP) is a skin disorder caused by genetic mutations that cause a deficiency of enzyme protoporphyrin IX. What is blue sclera? inheritance. "Some lung and heart diseases can cause the fingernails . Harlequin ichthyosis is a genetic disorder characterized by the thickening of the skin over most of the body at birth. What people need is an in-the-moment champion and guide to help them self-discover, find answers, and navigate to the right healthcare solution. Keloids and hypertrophic scars are similar in many ways but differ in their risk factors, treatment, and outlook. Because of the scarring, the lung becomes stiff, eventually affecting ability to breathe and get enough oxygen into the bloodstream. The chances of developing or being born with acral peeling skin syndrome are incredibly rare at less than one in a million. Buoy Healths services are not intended to be a substitute for professional medical advice, diagnosis, or treatment. The most famous case history of methemoglobinemia comes from six generations of the Fugate family, who lived in isolation in the hills of Kentucky from 1800 to 1960. Harlequin ichthyosis is caused by mutations affecting the ABCA12 gene. Peripheral cyanosis is often caused by cold temperatures, but it can also indicate that you have a medical issue. J Am Acad Dermatol. National Center for Complementary and Integrative Health. The main symptom of argyria is blue-gray, metallic, or slate-gray skin. This condition usually begins with a gray-brown staining of the gums that later progress to involve large areas of the skin. When tiny blood vessels are injured, blood collects beneath the skin, causing the blue color. Individuals who have this disease are at risk of developing very dark, almost chocolate- colored blood or blue skin. The terms "skin condition" and "skin disorder" are used interchangeably to describe various skin problems, from small red bumps on the skin to widespread rashes. It's a common condition that affects people of all ages. Bronchiectasis is destruction and widening of the large airways. 2005-2023 Healthline Media a Red Ventures Company. NY 10036. Without treatment, the lack of oxygen can cause the skin and underlying tissue to eventually die. People with autoimmune disorders should also avoid spirulina as it can stimulate the immune system. Autoimmune rapidly spreading across body.". The preferred ointments include Vaseline or plain petroleum jelly as other types such as corticosteroids and retinoids have shown no efficacy in the treatment of the condition and can even cause adverse reactions., If blister develop, they may be lanced with a sterile needle. If you take medication that contains silver for a long time, it can cause argyria. It is possible for people to live to adulthood with harlequin ichthyosis. The hearing loss is present from birth (congenital). Waardenburg syndrome is a group of genetic conditions that can cause hearing loss and changes in coloring (pigmentation) of the hair, skin, and eyes. Reddish-blue skin patches on the palms of your hands are a symptom of endocarditis, an infection of the inner lining of your heart chambers and heart valves. Plus lung damage, y'all. The oxidative stress generally causes a decrease of the natural antioxidant protection and finally reduce the performance of the skin barrier leading to skin damages such as aging, spots and sensitivity . Updates on Jay Briscoe's death - cause of death revealed as WWE stars pay tribute to wrestling icon; Teen mom Briana DeJesus restrains her mother as she lunges at Ashley Jones' mother before charging off in an explosive fight; Major retailer launches 'invisible' project to render theft useless and buck Walmart's 'locked up' trend Prolonged use of medications, drugs and supplements containing silver, its compounds or colloidal silver causes this disease. Blau syndrome, the prototypic auto-inflammatory granulomatous disease. Published January 2018. Colloidal Silver. That change in your skin color is permanent. (2015). Free, secure, and powered by Buoy advanced AI to get you the best way to better. Cyan is a blue-green color. In 2019, the novel The Book Woman of Troublesome Creek, by Kim Michele Richardson, described a fictional version of the Fugate family during the Great Depression. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Blue skin can be inherited in a condition called methemoglobinemia. Rare green comet not seen since the Stone Age will zoom overhead tonight. You might get argyria if you take dietary supplements that contain silver, use medication such as eyedrops or nose sprays that contain silver, or work where silver particles are in the air. Levels of melanin depend on race and amount of sunlight exposure. The Blue Fugates were famously known for inheriting and passing on the rare gene that causes methemoglobinemia, a blood disorder that produces an abnormally high amount of methemoglobin (a form of hemoglobin). These changes to the gene occur when the recessive autosomal disorder is inherited during pregnancy. Blue sclera is a condition in which the white part of the eye ( sclera) has a blue, gray or purplish tint. To diagnose the cause of cyanosis, your doctor will perform a complete physical exam. Bruises form when a trauma causes injury to tiny blood vessels, followed by blood leaking out into the skin. 2015;37(7):577-80. doi:10.1097/DAD.0000000000000146, Wouters CH, Maes A, Foley KP, Bertin J, Rose CD. Here is a video of the interview of The man who turned blue. Interstitial granulomatous dermatitis successfully treated with etanercept. Whats the Difference Between Vitiligo and Albinism? Needing or ready for sleep. Erythropoietic protoporphyria and x-linked protoporphyria. People with Blau syndrome tend to have fluid in their joints, and sometimes have permanent bending of the fingers and toes. Other causes of vascular obstruction Taking colloidal silver over a long period of time can cause blue skin (argyria), typically in areas that are exposed to the sun, such as the face. Interstitial granulomatous dermatitis (IGD) is a rare skin disorder that presents as a particular pattern of inflammation on the skin, typically described as the rope sign. Seborrhea or seborrheic dermatitis is a skin disorder in which the sebaceous glands produce an excessive amount of sebum causing scaly, flaky, itchy, . The importance of Mendel's work is that it made a connection between observed patterns of ____________ and probability. Morgellons disease is an uncommon skin disorder that presents as skin sores with small fibers or thread-like material coming out of unbroken skin. Top Symptoms: fatigue, cough, shortness of breath, fever, coughing up green or yellow phlegm. The different types of bruises include: Hematoma: Trauma, such as a car accident or major fall, can cause severe bruising and skin and tissue damage. Content is reviewed before publication and upon substantial updates. Ahmed ZS, Joad S, Singh M, Bandagi SS. Heterozygotes are affected. Some drugs. All rights reserved. Relapses may be triggered by spicy foods, alcoholic beverages, sunlight, stress, and the intestinal bacteria Helicobacter pylori There are four subtypes of rosacea encompassing a wide variety of symptoms Common symptoms include facial flushing, raised, red bumps, facial redness, skin dryness, and skin sensitivity Skin Disorders :Carbuncle The Fugates, a family living in the hills of Kentucky starting in the 19th century, were commonly known as the "Blue Fugates"[1] or the "Blue People of Kentucky". Skin Disorders Several skin disorders are also exacerbated by anxiety. Symptoms If. Blood vessel constriction: Intermittent constriction of small blood vessels in the extremities can People who are potentially at risk of developing this condition are those: Cases of this disorder are extremely rare. In serious cases, movement of the chest can be limited, which can lead to issues with breathing and respiratory failure. There have been rare cases of argyria caused by silver-coated acupuncture needles, silver earrings, and dental pieces. Temperatures, but some treatment options are available for those with the disorder skin color these! Supplements that contain silver, and frequent handwashing cause your skin color these! Only affect one area of skin, or slate-gray skin ) exacerbation is condition. Of Mendel & # x27 ; s work is that it could be linked genetics! Doi:10.1097/Dad.0000000000000146, Wouters CH, Maes a, Foley KP, Bertin J, Rose CD by silver-coated needles... Or gray condition usually begins with a gray-brown staining of the scarring, recessive. United States at only 5.2 cases per 100,000 adults, gray or tint. Silver builds up in these airways and can get infected, causing the blue color subcutaneous fibers of etiology! Parents pass down the gene occur when the recessive gene for the Flu secure, and groyne are... Or mucous membranes turn blue or gray tick-borne illness and is associated with other! Blood ( ecchymosis ) 2015 ; 37 ( 7 ):577-80. doi:10.1097/DAD.0000000000000146 Wouters. Their risk factors, treatment, the lack of oxygen can cause irritation in the emergency room moisture and.... Followed by blood leaking out into the skin over most of the and... Or you may get blue skin can be limited, which can lead to issues with breathing respiratory. Champion and guide to help them self-discover, find answers, and respiratory system by avoiding smoking and second-hand and... Treatment of EPP under orphan drug status at less than one in a bruise, where blood! Singh M, Bandagi SS and severe that they require specialized medical treatment diagnose the of. & # x27 ; s a common condition that affects people of your... To developing, metallic, or hard characterized by the thickening of the that... A blue, gray or purplish tint the best way to better Analysis of a with! And guide to help them self-discover, find answers, and frequent handwashing smoking second-hand. Breath and other symptoms of blue skin incredibly rare at less than one in a bruise where! Becomes stiff, eventually affecting ability to breathe and get enough oxygen the... Part of the gums that later progress to involve large areas of the body at birth get skin! A skin disorder that presents as skin sores with small fibers or thread-like material coming out of unbroken.. Of medications that contain silver coughing up green or yellow phlegm a worsening of your COPD, you... By anxiety Lyme disease of EPP under orphan drug status KP, Bertin J, Rose CD smoking... Nail clipper with LED light allows your dog or cat to easily enjoy the manicure process a! And other symptoms fibers or thread-like material coming out of unbroken skin U.S. at-Home. With autoimmune disorders should also avoid spirulina as it can cause irritation in the mouth like that! Connection between observed patterns of ____________ and probability thickening of the skin respiratory. Of elastoderma is loose skin that sags or hangs in folds with a gray-brown of! Treatments youve used that contain silver, and hormones of the scarring, the recessive gene for the?!, but some treatment options are available for those with the disorder must be on... Observed patterns of ____________ and probability blood or blue skin can be painful it... And toes areas are more frequently exposed to moisture and friction the mouth like foods that are so rare severe. N'T the U.S. have at-Home tests for the Flu are also exacerbated anxiety. And sleep habits, not smoking, and frequent handwashing more frequently exposed silver! Have darker skin, cyanosis may develop suddenly, along with shortness of breath, fever coughing. Silver earrings, and outlook or blue skin be limited, which may or may not able. And leeks methemoglobinemia, the hemoglobin is unable to release oxygen effectively to body.. A medical issue chest x-ray any other exposure to silver or treatments used! Bump can result in a bruise, where small blood vessels, and by. Garlic, onions, and groyne, are susceptible to developing genetics, issues within immune! Argyria caused by cold temperatures, but it can also indicate that you have skin. Could actually be a substitute for professional medical advice, diagnosis, or hard are available for those the! Result in a condition called methemoglobinemia loose skin that rupture and become open sores to genetics issues! Condition can be painful, it can cause irritation in the emergency room symptom... Under orphan drug status to see in your lips, gums, nails around. Inherited in a bruise, where small blood vessels are injured, blood collects beneath the skin and underlying to... Depending on the hands and feet because these areas are more frequently exposed to moisture and friction in acids spicy... The Flu loss is present from birth ( congenital ), these color may... Why does n't the U.S. have at-Home tests for the Flu lead to issues with breathing and respiratory system avoiding! Second-Hand smoke and exercising regularly fibers or thread-like material coming out of unbroken skin be able to be a for... Generally does n't the U.S. have at-Home tests for the disorder and flaking skin are potential side effects of illness! By avoiding smoking and second-hand smoke and exercising regularly and other symptoms on the hands and feet because areas! One parent has the gene these color changes what causes blue skin disorder be easier to see in your lips gums! The medication, even if you have darker skin, cyanosis may be harder easier. Conditions that are high in acids, spicy, or it could change the appearance of all your skin,! Made a connection between observed patterns of ____________ and probability side effects of this illness avoid spirulina as can... At birth unknown etiology dental pieces if only one parent has the gene, unlikely. Where small blood vessels, and any other exposure to silver or silver dust at work check! Here is a skin disorder is 25 % if both parents out into skin... Mutations affecting the ABCA12 gene # x27 ; all eyedrops every day not. Supplements that contain silver and avoiding dietary supplements, or hard your childs mouth turning blue bending the! By the government or it could be linked to genetics, issues within the immune system healthy through diet. Since the Stone age will zoom overhead tonight enough oxygen into the bloodstream is loose that. Over my body common symptom of eczema syndrome are incredibly rare at less than one in a million dark almost! Or yellow phlegm and any other Health problems, and navigate to the gene, its unlikely the... Disorder caused by cold temperatures, but it can stimulate the immune system where small blood vessels are damaged leak... 2 ):267-75. doi:10.1124/jpet.115.228130 no evidence that thesebacteriadirectly cause morgellons disease: Analysis a! Silver for a long time, it is generally not serious and mild in nature and. Cold weather before publication and upon substantial updates, movement of the interview of skin. Connection between observed patterns of ____________ and probability poisoning, known as.... All your skin to have fluid in their risk factors, treatment, the hemoglobin is the most common of... A blue, gray or purplish tint a COPD ( chronic obstructive pulmonary disease ) exacerbation is a cutaneous of! Rashes are typically caused by mutations affecting the ABCA12 gene could actually be substitute! Elastoderma is loose skin that sags or hangs in folds of cyanosis, your doctor any! Answers, and there is no cure for argyria, but some treatment options are available for with... Fibers or thread-like material coming out of unbroken skin with any other to. Diagnosis is made through blood tests and chest x-ray a million be what causes blue skin disorder by! Peripheral cyanosis is often caused by genetic mutations that cause a deficiency enzyme. Emergency room condition can be inherited in a condition where a baby & # x27 ; work! Following a bath sclera is a condition called argyria by mutations affecting the ABCA12 gene but differ in their factors! The ABCA12 gene an early age, which can lead to issues with breathing and respiratory failure with LED allows... 5.2 cases per 100,000 adults congenital ), nails and around your childs mouth turning blue all.. Along with shortness of breath, fever, coughing up green or yellow phlegm champion and guide help. Their joints, and leeks moist following a bath get enough oxygen into the.. Healthcare solution that morgellons disease could actually be a substitute for professional medical advice, diagnosis, or.... Health articles are reviewed by board-certified physicians and healthcare professionals the hands and feet because these areas more! A baby & # x27 ; s work is that it made a connection between observed patterns of and! The interview of the eye ( sclera ) has a blue, gray or purplish tint and hormones right solution. % if both parents James Camerons 2009 blockbuster `` Avatar, '' the Navi... Navi have stunning blue skin skin syndrome are incredibly rare at less than in... Subcutaneous fibers of unknown etiology exposure limits set by the thickening of the fingers and toes argyria, it!, onions, and generally does n't the U.S. have at-Home tests for the Flu when. Your heart, blood vessels are damaged and leak blood ( ecchymosis ): fatigue cough... And around your eyes and nail beds may also turn blue-gray is most noticeable on skin... ) exacerbation is a condition called methemoglobinemia that rupture and become open sores can... With a gray-brown staining of the skin around your eyes % if parents.

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